It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them.
Discovery of penicillin
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"Many difficulties were encountered in the early attempts to isolate and purify penicillin."
Shocking"The bacteriologist must be a patient man."
Strange & Unusual"The accidental contamination of my cultures by a mold was not an unusual event in a bacteriological laboratory. What was unusual was my decision to investigate the mold."
Strange & Unusual"I never thought of myself as a great man, just a man who made a great discovery."
Shocking"I was not looking for penicillin when I discovered it. I was looking for a better antiseptic."
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